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Mastocytoma
Mastocytomas are localized collections of mast cells. Typically .5 to 1.5 cm in diameter, they have a yellow-red-brown color. Stroking the lesion elicits an urticarial response, Darier's sign.
Extensive mast cell involvement of the skin is called urticaria pigmentosa.
Treatment:
- Solitary mastocytomas resolve without treatment.
- Most lesions present in early childhood are gone by age 10.
Treatment for Urticaria Pigmentosa
- H1 antihistamines, H2 antihistamines, disodium cromoglycate
- Topical steroids
- PUVA
- Case reports showing help from cyclosporine, nifedipine and pulse dye laser
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