Sarcoidosis
Sarcoidosis is a disease of unknown etiology characterized in the skin by red to violaceous papules and plaques with a granulomatous histology.
There is a tendency to systemic involvement with restrictive pulmonary disease and ocular involvement being common.
Skin disease shows many patterns including:
Lupus pernio:
violaceous plaques involving the nose, central face, and ears.
Scar sarcoidosis:
sarcoid skin lesions with a predilection to scars.
Papular sarcoidosis:
grouped red-brown papules, most common on the face and limbs.
Nodular sarcoidosis:
lesions are larger than papules and can tend to form plaques.
Erythema nodosum is a common presenting sign of sarcoidosis. Sarcoidosis is more common in African-Americans than in whites.
Treatment:
- Chloroquine and hydroxychloroquine maybe effective
- Thalidomide can also be considered
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